Table 1. Performance of PIRSS on the Validation Data Sets.
| Data setsa | Images, No. | AUC (95% CI) | % (95% CI) | |
|---|---|---|---|---|
| Sensitivity | Specificity | |||
| Overall | 1335 | 0.993 (0.983-1.000) | 91.9 (80.8-100) | 98.7 (97.1-100) |
| Normal | 378 | 0.992 (0.989-0.995) | 95.2 (92.6-97) | 96.7 (95.4-97.7) |
| Suspect | 115 | 0.980 (0.972-0.988) | 76.5 (68.0-83.3) | 98.2 (97.3-98.8) |
| Early KC | 137 | 0.996 (0.993-0.999) | 92.0 (86.2-95.5) | 99.1 (98.4-99.5) |
| KC | 446 | 0.999 (0.998-1.000) | 97.8 (95.9-98.8) | 99.2 (98.4-99.6) |
| Postoperative | 259 | 0.998 (0.996-1.000) | 98.1 (96.6-99.2) | 100 (99.6-100) |
Abbreviations: AUC, area under the receiver operator characteristic curve; KC, keratoconus.
a
Normal indicates normal cornea; suspect, suspected irregular cornea; early KC, early-stage KC; KC, keratoconus diagnosis; postoperative, myopic postoperative cornea.