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. 2020 Jan 10;318(3):H547–H557. doi: 10.1152/ajpheart.00367.2019

Table 2.

Summary of hemodynamic parameters calculated from the simulated echo measurements using the PISA method based on the average of four instances in systole

M&I P1 M&I P2 P2&P3 P2&P1
True PISA EROA, cm2 0.17 0.37 1.10 0.97
3D-echo PISA EROA, cm2 0.14 0.32 0.92 0.84
3D-HE PISA EROA, cm2 0.11 0.25 0.66 0.60
2D-A2ch PISA EROA, cm2 0.13 0.61 0.93 1.39
2D-A4ch PISA EROA, cm2 0.10 0.31 0.82 0.58
True PISA RVolMV, mL (%) 12.0 (−19) 30.6 (26) 91.4 (94) 88.4 (72)
3D-echo PISA RVolMV, mL (%) 10.3 (−30) 26.4 (95) 76.8 (63) 76.5 (48)
3D-HE PISA RVolMV, mL (%) 7.8 (−47) 21.1 (−13) 54.7 (16) 54.9 (7)
2D-A2ch PISA RVolMV, mL (%) 9.6 (−35) 51.3 (111) 77.3 (64) 127.5 (147)
2D-A4ch PISA RVolMV, mL (%) 7.2 (−52) 26.3 (8) 68.6 (45) 53.4 (4)

Values in parenthesis denote the relative percentage error with respect to the ground truth values (i.e., FSI-RVolMV). 2D, two-dimensional; 3D, three-dimensional; A2ch, apical two-chamber; A4ch, apical four-chamber; echo, echocardiography; EROA, effective regurgitant orifice area; FSI, fluid-structure interaction; M&I, marginal and intermediate; MV, mitral valve; PISA, proximal isovelocity surface area; RVol, regurgitant volume; HE, hemielliptic.