Fig. 5.

A: nanoinjections of muscimol into the dorsal medial hypothalamus (DMH) had no effects on lumbar sympathetic nerve activity (LSNA) or heart rate (HR) in obesity-prone (OP, n = 4), obesity-resistant (OR, n = 5), or control (CON, n = 5) rats. Nanoinjections of muscimol [but not SHU9119 or artificial cerebrospinal fluid (aCSF)] into the DMH decreased MAP (ANOVA, time effect, P < 0.001), but the hypotensive response did not differ between groups. B: nanoinjections of aCSF into the DMH had no effects on LSNA, HR, or MAP in OP (n = 8), OR (n = 5), or CON (n = 6) rats.