Fig. 8.

Intracerebroventricular insulin infusion increases mean arterial pressure (MAP, A) and baroreflex control of heart rate (HR, B) in conscious obesity-prone (OP, n = 6), but not obesity-resistant (OR, n = 5) and control (CON, n = 5), rats. A: baseline MAP was not different between groups. In OP, but not OR or CON, rats, intracerebroventricular insulin increased MAP. B: HR baroreflex gain [absolute values (insets)] was lower in OP than CON or OR rats. Intracerebroventricular insulin increased baroreflex gain only in OP rats to levels higher than in OR or CON rats. OP, open and closed gray triangles, bars, and lines; OR, open solid squares and bars and solid and dashed black lines; CON, open and closed solid circles and bars. *P < 0.05 vs. OR and CON under the same condition; †P < 0.05 vs. baseline (by 2-way repeated-measures ANOVA).