Table 2.

Effect of intracerebroventricular insulin infusion on HR and baroreflex parameters in conscious OP, OR, and CON rats

	OP (n = 6)		OR (n = 5)		CON (n = 5)
	Baseline	Insulin	Baseline	Insulin	Baseline	Insulin
Maximum, beats/min	417 ± 17	500 ± 12*	459 ± 24	470 ± 7	452 ± 20	468 ± 18
Minimum, beats/min	259 ± 11	286 ± 7*†	237 ± 12	245 ± 15	272 ± 11	259 ± 15
Range, beats/min	162 ± 13	206 ± 10	222 ± 23	225 ± 13	181 ± 29	209 ± 20
BP50, mmHg	95 ± 2	99 ± 2	91 ± 5	100 ± 5	91 ± 3	95 ± 2
Width, mmHg	11.7 ± 1.2	9.7 ± 0.8	12.5 ± 1.7	12.8 ± 1.5	9.2 ± 0.9	11.6 ± 1.4
HR, beats/min	322 ± 7	349 ± 10	324 ± 15	339 ± 14	331 ± 6	341 ± 15

Values are means ± SE; n, number of rats. HR, heart rate; CON, control; OR, obesity-resistant; OP, obesity-prone; BP₅₀, arterial pressure at the midpoint of HR range.

^*P < 0.05 vs. basal;

^†P < 0.05 vs. CON and OR.