Olfactory receptor-78 (Olfr-78) expression in colitis models. A: colonic Olfr-78 expression is reduced in mouse models of 2,4,6-trinitrobenzenesulfonic acid (TNBS)-induced colitis, where real-time RT-PCR was performed on total RNA extracted from mucosal scrapings of distal colons from control and TNBS-treated mice using Olfr-78-specific primers and normalized with GAPDH RNA (n = 4, **P < 0.01). B: colonic Olfr-78 expression is reduced in mouse model of dextran sodium sulfate (DSS)-induced colitis, where real-time RT-PCR was performed on total RNA extracted from mucosal scrapings of distal colons from control and DSS-treated mice using Olfr-78 gene-specific primers and normalized with GAPDH mRNA (n = 4, **P < 0.01). C and D: G protein-coupled receptor (GPR) 43/41 expression is not altered in TNBS- and DSS-induced mouse colitis models. Real-time RT-PCR was performed on RNA isolated from proximal and distal colons of control and DSS- and TNBS-treated mice using GPR-43/41 gene-specific and GAPDH primers (n = 4, *P < 0.05).