Table. General Information and Clinical Features of 33 Newborns With Mothers With COVID-19 Pneumonia.
Variable | Neonates with SARS-CoV-2, No. (%) | Patients with SARS-CoV-2 | |||
---|---|---|---|---|---|
No (n = 30) | Yes (n = 3) | Patient 1 | Patient 2 | Patient 3 | |
Male | 16 (53) | 3 (100) | Yes | Yes | Yes |
Preterm | 3 (10) | 1 (33) | GA: 40 wk | GA: 40 wk + 4 d | GA: 31 wk + 2 d |
Small for gestational age | 2 (7) | 1 (33) | No; 3250 g | No; 3360 g | No; 1580 g |
Asphyxia | 1 (3) | 1 (33) | No | No | Yes |
Symptoms and complications | |||||
Fever | 0 | 2 (67) | Yes | Yes | No |
Pneumonia | 0 | 3 (100) | Yes | Yes | Yes |
Respiratory distress syndrome | 3 (10) | 1 (33) | No | No | Yes |
Shortness of breath | 3 (10) | 1 (33) | No | No | Yes |
Cyanosis | 2 (7) | 1 (33) | No | No | Yes |
Feeding intolerance | 2 (7) | 1 (33) | No | No | Yes |
Laboratory test, median (range) | |||||
White blood cell count, cells/μL | 9800 (6100-22 700) | 19 200 (8600-20 400) | 8600 | 19 200 | 20 400 |
Lymphocyte count, cells/μL | 4300 (1500-10 700) | 2600 (800-3100) | 3100 | 2600 | 800 |
Platelets, ×103/μL | 184 (116-303) | 245 (230-265) | 245 | 265 | 230 |
Creatine kinase isoenzymes, U/L | 13 (22.5-43) | 31 (18-39) | 18 | 31 | 39 |
Aspartate aminotransferase | 27.5 (12-45) | 24 (8-63) | 8 | 24 | 63 |
Alanine aminotransferase | 21 (9-95) | 17 (11-88) | 11 | 17 | 88 |
Treatment | |||||
Mechanical ventilation | 0 | 1 (33) | No | No | Yes |
Antibiotic | 6 (20) | 1 (33) | No | No | Yes |
Duration of neonatal intensive care unit, median (range), d | 0 (0-6) | 4 (2-11) | 2 | 4 | 11 |
Death | 0 | 0 | No | No | No |
Maternal features | |||||
Fever on admission | 7 (23) | 1 (33) | Yes | No | No |
Postpartum fever | 4 (13) | 1 (33) | Yes | No | No |
Cough | 9 (30) | 1 (33) | No | Yes | No |
Intensive care unit admission | 0 | 0 | No | No | No |
Pneumonia per computed tomography diagnosis | 30 (100) | 3 (100) | Yes | Yes | Yes |
Nasopharyngeal swab | 30 (100) | 3 (100) | Yes | Yes | Yes |
Delivered by cesarean delivery | 23 (77) | 3 (100) | Yes | Yes | Yes |
Premature rupture of membranes | 2 (7) | 1 (33) | Yes | No | No |
Abbreviations: COVID-19, coronavirus disease 2019; GA, gestational age; SARS-CoV-2, severe acute respiratory syndrome coronavirus 2.
SI conversion factors: To convert the white blood cells and lymphocytes to cells × 109/L, multiply by 0.001; to convert platelets to cells × 109/L, multiply by 1.0; to convert creatinine, aspartate aminotransferase, and alanine aminotransferase to μkat/L, multiply by 0.0167.