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. 2020 Mar 20;11:97. doi: 10.3389/fendo.2020.00097

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Copyright © 2020 Aldiss, Lewis, Lupini, Bloor, Chavoshinejad, Boocock, Miles, Ebling, Budge and Symonds.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Exercise training (Ex) regulates thermogenic genes in a depot-specific manner. (A–C) thermogenic mRNA in BAT, PVAT, and IWAT, (D,E) histological analysis of BAT and lipid droplet size and (F,G) histological analysis of WAT and adipocyte size. Data expressed as mean ± SEM, n = 4–5 per group. Adipocyte/lipid droplet area quantified using Adiposoft (BAT-C, n = 8,949 and Ex, n = 8,234; WAT-C, n = 750 and Ex – n = 555). For comparison, data was analyzed by Students t-test. Significance denoted as ^*p < 0.05 and ^****p < 0.0001.