Table 1. Baseline Demographic, Clinical, and Imaging Data.
| Characteristic | Mean (SD) | P Value | ||||||
|---|---|---|---|---|---|---|---|---|
| Overall (N = 257) | Married (n = 145) | Unmarried (n = 77) | Widowed (n = 35) | UM-M | W-M | W-UM | ||
| Age, y | 73.5 (6.1) | 73.3 (5.8) | 72.1 (5.5) | 77.6 (6.6) | .36 | <.001 | <.001 | |
| Women, No. (%) | 153 (59.5) | 66 (45.5) | 56 (72.7) | 31 (88.6) | <.001 | <.001 | .10 | |
| Hollingshead scorea | 26.5 (14.5) | 24.4 (14.0) | 28.1 (15.1) | 31.4 (13.7) | .16 | .03 | .50 | |
| Geriatric Depression Scale score | 3.1 (2.8) | 2.8 (2.5) | 3.6 (3.1) | 3.4 (3.4) | .11 | .48 | .94 | |
| Depression history, No. (%) | 39 (15.2) | 20 (13.8) | 13 (16.9) | 6 (17.1) | .68 | .82 | >.99 | |
| β-amyloid burden, neocortical PiB PVC DVRb | 1.35 (0.38) | 1.36 (0.40 | 1.35 (0.37) | 1.30 (0.33) | .99 | .63 | .74 | |
| PACC z score | 0.03 (0.63) | 0.08 (0.60) | 0.02 (0.66) | −0.13 (0.65) | .79 | .18 | .47 | |
| MMSE score | 29.1 (1.0) | 29.1 (0.9) | 29.1 (1.1) | 28.8 (1.3) | .92 | .17 | .35 | |
| FCSRT scorec | 47.7 (0.9) | 47.7 (0.8) | 47.9 (1.1) | 47.6 (1.2) | >.99 | .79 | .84 | |
| Logical Memory score | 13.9 (3.2) | 13.7 (2.8) | 14.2 (3.5) | 14.6 (3.6) | .58 | .28 | .77 | |
| Digit Symbol Substitution Test scored | 48.3 (9.9) | 50.0 (9.1) | 46.7 (11.4) | 44.1 (8.8) | .09 | <.001 | .45 | |
| Follow-up time, y | 3.1 (0.2) | 3.1 (0.2) | 3.1 (0.2) | 3.1 (0.2) | .40 | .94 | .82 | |
Abbreviations: DVR, distribution volume ratio; FCSRT, Free and Cued Selective Reminding Test; MMSE, Mini-Mental State Examination; PACC, Preclinical Alzheimer Cognitive Composite; PiB, Pittsburgh compound B; PVC, partial volume correction; UM-M, unmarried compared with married; W-M, widowed compared with married; W-UM, widowed compared with unmarried.
a
Higher score indicates lower socioeconomic status.
b
Available for 254 participants.
c
Available for 235 participants.
d
Available for 256 participants.