Figure 1. . Mean parasitemia clearance during chloroquine/primaquine regimen according to SLCO2B1 genotypes.

Generalized estimating equations method with age, gender, co-medication, parasitemia baseline level and genetic ancestry as covariates; gene*time p_FDR = 0.002 and d = 0.89. In the right circle, it was highlighted the mean parasitemia clearance in the days 2 and 3. On day 2, AA genotype showed a higher parasitemia clearance rate over treatment time than GG genotypes. Mean parasitemia means are presented as parasites/ul (for details, see ‘Patients & methods’ section).