Table 2.
Main features of subjects participating in the study.
| Parameters |
Co (n = 22) |
DM (n = 18) |
TB (n = 21) |
TB+DM (n = 11) |
Overall p-value |
|---|---|---|---|---|---|
| Age (years) | 45 (35–62) | 54 (51–61) | 41 (34–59) | 50 (41–62) | n.s. |
| Sex (F/M) | 9/13 | 10/8 | 8/13 | 6/5 | n.s. |
| BCG (%) | 95.4 | 78.9 | 76.2 | 45.5*#& | 0.001 |
| BMI (kg/m2) | 27.0 (25.9–29.6) | 28.0 (25.1–31.5) | 20.9 (19.4–23.9)* | 26.9 (23.4–31.9)& | <0.0001 |
| Glycemia (mg/dl) [r.v: 70–100] |
89.5 (84.3–106) |
111* (94.5–129) |
87.0 (81.0–104) |
213*,
#,
& (161–285) |
<0.0001 |
| HbA1C (%) [r.v: 4.8-6] |
5.5 (5.0–5.8) |
7.5* (6.0–10) |
5.8 (5.4–6.3) |
9.7*,
& (7.0–11) |
<0.0001 |
| Insulin (μIU/ml) [r.v: 2.6-25] |
6.7 (5.4–9.8) |
7.4 (5.7–13) |
7.0 (3.9–8.6) |
14*,& (6.4–29) |
0.0003 |
| HOMAIR [r.v: ≤ 3.2] |
1.43 (1.08–2.12) |
3.22* (1.32–4.45) |
1.51 (0.832–2.20) |
6.51*,
#,
& (2.31–15.8) |
0.0003 |
| ESR (mm/1° hs) [r.v: 1-15] |
5.0 (2.3–9.3) |
10.0* (7.8–20.5) |
57.5* (34.5–89.5) |
60.0*,# (36.0–92.0) |
<0.0001 |
Co, controls; DM, patients with type 2 diabetes mellitus; TB, patients with pulmonary tuberculosis; TB+DM, patients with pulmonary tuberculosis and type 2 diabetes mellitus; n.s., not significant; F, female; M, male; BCG, Bacillus Calmette-Guerin vaccination; BMI, body mass index. rv, reference values; HOMAIR index, [insulin (μIU/ml)*glycemia (mmol/L)]/22.5; ESR, Erythrocyte Sedimentation Rate. Results are shown as median (25-75 percentiles).
*
different from HCo, p < 0.05;
#
different from DM, p < 0.05;
&
different from TB, p < 0.05.