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. 2020 Mar 20;11:338. doi: 10.3389/fphar.2020.00338

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Copyright © 2020 Li, Wu, Chen, Wang, Guo, Zhao, Zhao, Wang, Liu and Yan

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) Metabolic pathway analysis of IRFV-treated mice from MetaboAnalyst 3.0. The impact is the pathway impact value calculated from pathway topology analysis. Phenylalanine, tyrosine, and tryptophan biosynthesis (a); d-glutamine and d-glutamate metabolism (b); alanine, aspartate, and glutamate metabolism (c); arginine and proline metabolism (d); glycine, serine, and threonine metabolism (e); taurine and hypotaurine metabolism (f); phenylalanine metabolism (g); and valine, leucine, and isoleucine biosynthesis (h). The details of the pathways are shown in panel B.