Table 4.
Multivariate logistic regression model of risk factors for over-N-staging and under-N-staging in rectal cancer
| Characteristics | Over-N-staging | Under-N-staging | ||||
|---|---|---|---|---|---|---|
| OR | 95% CI | P Value | OR | 95% CI | P Value | |
| CEA | 1.012 | 1–1.024 | 0.06 | 1.002 | 0.988–1.015 | 0.792 |
| CA199 | 0.996 | 0.99–1.001 | 0.147 | 1 | 0.998–1.002 | 0.847 |
| BMI | 0.953 | 0.88–1.031 | 0.232 | 1.063 | 1–1.129 | 0.05 |
| WBC | 1.174 | 1.007–1.368 | 0.041 | 1.038 | 0.888–1.214 | 0.641 |
| HB | 0.993 | 0.977–1.009 | 0.383 | 0.993 | 0.978–1.009 | 0.411 |
| PLT | 1 | 0.996–1.003 | 0.838 | 1.002 | 0.998–1.006 | 0.33 |
| ALB | 1.002 | 0.953–1.053 | 0.953 | 1.027 | 0.976–1.082 | 0.306 |
| Tumor Location | 0.738 | 0.875 | ||||
| Upper | 1.216 | 0.629–2.351 | 0.56 | 1.157 | 0.613–2.184 | 0.653 |
| Middle | 1.322 | 0.638–2.739 | 0.453 | 1.002 | 0.493–2.036 | 0.995 |
| Low | 1 | 1 | ||||
| Histological Subtype | 0.285 | < 0.001 | ||||
| Classic adenocarcinoma | 1 | 1 | ||||
| Mucinous adenocarcinoma | 0.533 | 0.168–1.686 | 4.049 | 1.876–8.772 | ||
| Tumor Size | 1.434 | 1.223–1.680 | < 0.001 | 0.953 | 0.806–1.126 | 0.572 |
| Bowel Obstruction | < 0.001 | 0.596 | ||||
| No | 1 | 1 | ||||
| Yes | 3.494 | 1.797–6.794 | 1.243 | 0.556–2.776 | ||
Abbreviations: CEA carcinoembryonic antigen, BMI body mass index, WBC white blood cell, HB hemoglobin, PLT plate, ALB albumin