Table 2.
Comparison of baseline characteristics of high and low risk individuals based on Astro-CHARM and Pooled Cohort Estimator
| Characteristics | Astro-CHARM | PCE | ||
|---|---|---|---|---|
|
Low Risk N = 343 |
High Risk N = 43 |
Low Risk N = 306 |
High Risk N = 80 |
|
| Gender | ||||
| Male | 51.9% (178) | 76.7% (33) | 47.4% (145) | 82.5% (66) |
| Female | 48.1% (165) | 23.3% (10) | 52.6% (161) | 17.5% (14) |
| Weight (kg) | 73 ± 15 | 74 ± 14 | 74 ± 15 | 72 ± 13 |
| Height (cm) | 162 ± 11 | 165 ± 10 | 161 ± 11 | 166 ± 10 |
| Age (years) | 48 ± 7 | 55 ± 7 | 47 ± 6 | 57 ± 6 |
| Hypertensive | ||||
| Yes | 44.6% (153) | 53.5% (23) | 44.4% (136) | 50% (40) |
| No | 55.4% (190) | 46.5% (20) | 55.6% (170) | 50% (40) |
| Diabetic | ||||
| Yes | 11.1% (38) | 53.5% (23) | 8.8% (27) | 42.5% (34) |
| No | 88.9% (305) | 46.5% (20) | 91.2% (279) | 57.5% (46) |
| Current Smoker | ||||
| Yes | 11.1% (38) | 39.5% (17) | 9.2% (28) | 33.8% (27) |
| No | 88.9% (305) | 60.5% (26) | 90.8% (278) | 66.2% (53) |
| Family History of Myocardial infarction | ||||
| Yes | 28.6% (98) | 46.5% (20) | 32% (98) | 25% (20) |
| No | 71.4% (245) | 53.5% (23) | 68% (208) | 75% (60) |
| Coronary Artery Calcium (Agatston) | 9.9 ± 46.42 | 204.2 ± 546.76 | 15.5 ± 73.87 | 93 ± 400.79 |
| Total Cholesterol (mg/dL) | 178 ± 37 | 178 ± 50 | 175 ± 39 | 187 ± 37 |
| HDL Cholesterol (mg/dL) | 53 ± 39 | 45 ± 10 | 53 ± 41 | 45 ± 11 |
| Systolic Blood Pressure (mmHg) | 137 ± 20 | 155 ± 21 | 137 ± 20 | 148 ± 22 |
Astro-CHARM Astronaut Cardiovascular Health and Risk Modification; PCE Pooled Cohort Equation
Low-Risk = < 7.5% estimated 10 years risk; High-Risk = ≥7.5% estimated 10 years risk