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. 2020 Mar 27;18:75. doi: 10.1186/s12916-020-01530-z

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© The Author(s) 2020

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Meta-analysis of the changes in blood pressure with combination versus monotherapies (a, b) or different combination therapies (c, d). Combination versus monotherapy for change in systolic (a) and diastolic (b) blood pressures. Comparisons of different combination therapies for change in systolic (c) and diastolic (d) blood pressures