Fig. 5.

MiR-124-5p overexpression reversed the effect of TSA. a Apoptosis of cardiomyocytes was evaluated using Annexin/VI-PI staining under TSA treatment and miR-124-5p mimic transfection. b, c MDA and LDH amounts in cardiomyocytes were analysed using commercial kit. d The ROS of cardiomyocytes was detected using commercial kit and flow cytometry. e JC-1 staining was used to evaluate the MMP. f Western blot was carried out to detect the apoptotic protein expression such as bax, cytoplasma cyt-c, cleaved caspase3, and bcl-2. *p < 0.05