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. 2019 Sep 11;12(9):e009047. doi: 10.1161/CIRCIMAGING.119.009047

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Figure 1. — Surrogates for right ventricle (RV)-arterial coupling and their association with single-beat end-systolic elastance (Ees)/arterial elastance (Ea) in patients with pulmonary hypertension. A, Surrogates were compared with data obtained from invasively measured single-beat pressure-volume loops in the study cohort. B, Tricuspid annular plane systolic excursion (TAPSE)/systolic pulmonary artery pressure (PASP), fractional area change (FAC)/mean pulmonary artery pressure (mPAP), RV area change/end-systolic area (ESA), and stroke volume (SV)/ESA (all measured by echocardiography except mPAP [right heart catheterization] and SV [cardiac magnetic resonance]) showed significant associations with invasively measured single-beat Ees/Ea. No association of Ees/Ea with TAPSE/pulmonary artery acceleration time (ρ=−0.016; P=0.926) and PASP/ESA (ρ=−0.015; P=0.924) was evident. Pmax indicates maximum pressure of an isovolumic beat.