Figure 7. Mitochondrial cross-section area distribution.
Representative electron microscopy micrographs for all treatment groups showing sections of white (A) and red (E) quadriceps. The frequency distribution of the mitochondrial cross-section area is shown for the white quadriceps (WQ) in (B) WT, (C) KO, and (D) OE mice, and for the red quadriceps (RQ) in (F) WT, (G) KO, and (H) OE mice. Data are presented as mean ± SEM of 6 separate micrographs per group. The white bar in each picture represents 2 μm. Abbreviations: WT, wild type; KO, PGC-1α knock-out mice; OE, PGC-1α overexpressing mice; Ctl: control; Simv, simvastatin.