Fig. 1. Overview of targets typically modulated by anti-allergic drugs.

Figure shows a schematic T cell with relevant transmembrane receptors and ion channels inserted into the plasma membrane. The cytosol contains different signaling and metabolic pathways and a nucleus containing DNA and relevant transcription factors. The different anti-allergic and immunosupressive drugs and novel experimental substances (red font) and their targeted structures (red arrows) are depicted. Messenger RNA targeted by a DNAzyme is shown in blue. (For interpretation of the references to color in this figure legend, the reader is referred to the web version of this article.)