Table 3.
Relationship between mortality and patients’ clinical and treatment factors
| Parameter | Death cases (n = 8) | Survived cases (n = 110) | p valuea |
|---|---|---|---|
| Age, years | 1.8 (0.6–2.8) | 0.7 (0.2–1.8) | 0.13 |
| Male, n (%) | 3 (37.5) | 65 (59.1) | 0.28* |
| Duration of PICU stay (days) | 19.5 (8.3–33.0) | 5.0 (4.0–10.3) | 0.019 |
| Possible risk factors | |||
| Sick contact, n (%)b | 6 (75.0) | 44 (40.0) | 0.06 |
| Passive smoking exposure, n (%) | 0 | 9 (8.2) | 0.52* |
| Presence of older siblings, n (%) | 0 | 42 (38.2) | 0.049* |
| Multiple pregnancy, n (%) | 1 (12.5) | 11 (10.0) | 0.59* |
| Prematurity <37 weeks, n (%) | 3 (37.5) | 32 (29.1) | 0.44* |
| Chronic lung disease, n (%) | 2 (25.0) | 25 (22.7) | 0.59* |
| Congenital heart disease, n (%) | 2 (25.0) | 20 (18.2) | 0.46* |
| Neurodevelopmental conditions, n (%) | 6 (75.0) | 21 (19.1) | 0.002 |
| Chromosomal and genetic diseases, n (%) | 5 (62.5) | 13 (11.8) | 0.002 |
| Bacterial co-infections, n (%) | 3 (37.5) | 11 (10.0) | 0.05* |
| Treatments | |||
| IPPV, n (%) | 8 (100) | 23 (20.9) | <0.001 |
| NIV, n (%) | 3 (37.5) | 46 (41.8) | 0.56* |
| Systemic corticosteroids, n (%) | 4 (50.0) | 32 (29.1) | 0.25* |
IPPV intermittent positive pressure ventilation, NIV non-invasive ventilation
aAnalyzed by Fisher’s exact test (indicated by *) or χ2 tests for categorical variables and the Mann–Whitney U-test for numerical variables
bSick contact was defined as the exposure of our patients to subjects with symptoms of respiratory tract infections in the same household, class, or inpatient ward within one week from their onset of RSV infection