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. 2020 Mar 20;11:192. doi: 10.3389/fgene.2020.00192

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Copyright © 2020 Di, Di, Fu, Tang, Liu, Lei, Gu, Liu and Sun.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Detection performance of the nine-miRNA signature in GSE29622 data. (A) Risk grade analysis of the nine-miRNA signature of CRC. Risk grade of miRNA signature (Top); duration of cases (Middle); low- and high-risk clusters for the nine miRNAs (Bottom). (B) Survival analysis of the high-risk cluster and the low-risk cluster with Kaplan–Meier curves. (C) Detection effectiveness of the nine-miRNA signature for survival time. ROC curves of the nine-miRNA signature were used to predict 1- to 10-year survival. Independent detection power (efficiency) of individual miRNAs in the nine-miRNA signature. (D) hsa-miR-148a, (E) hsa-miR-210, (F) hsa-miR-200a, (G) hsa-miR-338c, (H) hsa-miR-101, (I) hsa-miR-29c, (J) hsa-miR-424, (K) hsa-miR-92a, and (L) hsa-miR-492. The x-axis represents overall survival time, whereas the y-axis indicates OS probabilities.