Table 1.
Baseline characteristics of study patients
| Characteristic | Patient A | Patient B | Patient C | Patient D |
|---|---|---|---|---|
| Age | 22 | 39 | 21 | 39 |
| Sex (female) | Yes | No | Yes | No |
| BMI (kg·m−2) | 25.5 | 33.2 | 28.6 | 24.3 |
| Aboriginal descent | Yes | Yes | Yes | No |
| Comorbidities | ||||
| Obesity | No | Yes | Yes | No |
| Smoking | No | No | Yes | No |
| Ethanol use | No | Yes | No | No |
| Vital signs on presentation | ||||
| Mean arterial pressure (mmHg) | 45 | 98 | 74 | 65 |
| Respiratory Rate (breaths·min−1) | 30 | 48 | 38 | 23 |
| Heart rate (beats·min−1) | 102 | 129 | 134 | 113 |
| Temperature (°C) | 38 | 38.9 | 39.6 | 39.2 |
| Organ dysfunction (ICU admission) | ||||
| Creatinine (µmol·L−1) | 68 | 473 | 77 | 86 |
| AST (U·L−1) | 15 | 60 | 62 | 20 |
| Bilirubin (µmol·L−1) | 11 | 8 | 11 | 7 |
| WBC (cell count ×10−9·L−1) | 27.9 | 15.5 | 38.6 | 7 |
| Lactate (mmol·L−1) | - | 2.3 | 4.1 | 1.8 |
| APACHE II score | 19 | 26 | 20 | 18 |
| Duration of illness | ||||
| Symptoms to hospital admission (days) | 9 | 3 | 14 | 7 |
| Admission to tracheal intubation (hr) | 6 | 3 | 48 | 70 |
| Time until appropriate antimicrobials administered (hr) | 24 | 12 | 48 | 78 |
| Systemic corticosteroids within 48 hr of mechanical ventilation | Yes | Yes | No | Yes |
| Norepinephrine use during hospital admission (days) | 13 | 1 | 9 | 3 |
| Vasopressin use during hospital admission (days) | 12 | 1 | 13 | 1 |
| ECMO configuration (I-inflow, R-return) | I:19Fr LCFV + 17Fr RIJ, R:19Fr RCFV | I/R: 31Fr RIJ bicaval dual lumen | I/R: 31 Fr RIJ bicaval dual lumen + I: 21Fr RCFV | I: 24 Fr RIJ + 22 Fr LCFV, R: 23 Fr RCFV |
APACHE II = acute physiology and chronic health evaluation II; AST = aspartate aminotransferase; BMI = body mass index; ECMO = extracorporeal membrane oxygenation; Fr = French; ICU = intensive care unit; LCFV = left common femoral vein; RCFV = right common femoral vein; RIJ = right internal jugular vein; WBC = white blood cell