Table 2.

Severity of ARDS prior to initiation of ECMO

	Patient A	Patient B	Patient C	Patient D
Ventilation and gas exchange
Highest FiO2	1.0	1.0	1.0	1.0
Trough PaO2/FiO2 ratio	58	61	55	44
Highest PEEP administered (cm H2O)	16	24	12	14
Lowest pH	7.13	7.06	7.17	6.99
Highest PaCO2, (mmHg)	73	78	46	102
Tidal volume mL·kg−1 PBW	5.1	7.6	6.3	7.1
Highest peak/plateau airway pressure (cm H2O)	50/-	40/-	-/33	46/35
Quadrants of chest radiograph affected (number)	4	4	4	4
Murray lung injury score	4	2.75	3.5	3.5
Adjunctive/Rescue therapy
Neuromuscular blockade within 48 hr of mechanical ventilation	Yes	Yes	Yes	Yes
Recruitment maneuvers	No	Yes	No	Yes
Inhaled nitric oxide	Yes	No	No	Yes
Prone positioning	No	No	No	Yes
Airway pressure release ventilation	No	Yes	No	No
Sodium bicarbonate intravenous infusion	Yes	Yes	No	Yes
Hours of mechanical ventilation prior to starting ECMO	42	58	24	90
ECMO retrieval	No	Yes	Yes	No

ARDS = acute respiratory distress syndrome; ECMO = extracorporeal membrane oxygenation; F_iO₂ = fraction of inspired oxygen; P_aO₂ = partial pressure of oxygen; P_aCO₂ = partial pressure of carbon dioxide; PBW = predicted body weight; PEEP = positive end-expiratory pressure