Table 4.
Patient A | Patient B | Patient C | Patient D | |
---|---|---|---|---|
Outcomes | ||||
Hospital length of stay (days) | 58 | 31 | 87 | 33 |
Duration of mechanical ventilation (days) | 19 | 18 | 52 | 25 |
ECMO duration (days) | 12 | 8 | 23 | 7 |
ICU length of stay (days) | 22 | 22 | 55 | 27 |
Survival to hospital discharge | Yes | Yes | Yes | Yes |
CPC status at hospital discharge | 1 | 1 | 2 | 1 |
Adverse events | ||||
Neurologic | - | Mycotic cerebral vasculitis | Anoxic cerebral injury | - |
Respiratory | - | - | Tension pneumothorax | Re-intubation |
Cardiovascular | Atrial dysrhythmias | - | - | Right ventricular dysfunction |
Gastrointestinal | - | - | Upper gastro-intestinal bleeding | Upper gastro-intestinal bleeding |
Transfusion requirements | ||||
PRBC, units/ICU days | 0.05 | - | 0.29 | 0.48 |
FFP (500 mL doses)/ICU days | 0.27 | - | - | - |
Platelets, total* | - | - | - | 3 doses |
CPC = cerebral performance category (1 = good cerebral performance, 2 = moderate cerebral disability, 3 = severe cerebral disability, 4 = coma/vegetative state, 5 = brain death);22 ECMO = extracorporeal membrane oxygenation; FFP = fresh frozen plasma; ICU = intensive care unit; PRBC = packed red blood cells. *One adult dose is a pool of six whole blood-derived platelets