Table 1.
No | Sex, Age | Disease | Clinical characteristics of RWS |
---|---|---|---|
0 | M, 76 | PMF | Recurrent fever, biological inflammatory syndrome and ARDS |
1 [17] | F, 59 | Post-PV MF | Respiratory distress, severe anemia requiring transfusion and symptomatic splenomegalia |
2 [17] | F, 69 | Post-PV MF | Respiratory distress with septic shock-like syndrome |
3 [17] | M, 44 | Post-PV MF | Respiratory distress associated with pleural and pericardial effusion |
4 [17] | M, 64 | PMF | Recurrent fever and recurrence of PMF symptoms (fatigue, pruritus, night sweats, splenomegalia with splenic infarction) |
5 [17] | F, 56 | Post-PV MF | Disseminated intravascular coagulation-like syndrome |
6 [18] | F, 70 | Post-PV MF | Recurrent fever, dyspnea, diarrhea and accelerated splenomegalia |
F female, M male, MF primary myelofibrosis, post-PV MF post polycythemia vera myelofibrosis, RWS ruxolibinib withdrawal syndrome, PMF primary myelofibrosis, ARDS acute respiratory distress syndrome