TABLE 6.
Parameters | Median (95%CI) |
Prevalence | 14.9(12.3−17.8) |
Test A | |
DSe | 59.6(49.6−68.8) |
DSp | 96.2(94.4−97.6) |
PPV | 73.2(63.0−82.1) |
NPV | 93.1(91.0−95.0) |
Test B | |
DSe | 99.8(97.7−100) |
DSp | 100(99.6−100) |
PPV | 99.8(97.6−100) |
NPV | 100(99.6−100) |
Test C | |
DSe | 99.8(97.6−100) |
DSp | 100(99.6−100) |
PPV | 99.8(97.5−100) |
NPV | 100(99.6−100) |
§The model described by Lim et al. (2013) and available online at http://mice.tropmedres.ac/publication.aspx was implemented. DSe: diagnostic sensitivity, DSp: diagnostic specificity, PPV: positive predictive value, NPV negative predictive value, Test A: qPCR (Smythe et al., 2002), Test B: qPCR multiplex presented here, Test C: sequencing analysis of the amplification products obtained.