1 Failure to control bleeding |
13 |
1551 |
Risk Difference (M‐H, Random, 95% CI) |
‐0.02 [‐0.07, 0.02] |
1.1 EVS compared with vasopressin |
1 |
64 |
Risk Difference (M‐H, Random, 95% CI) |
‐0.23 [‐0.44, ‐0.03] |
1.2 EVS compared with terlipressin |
1 |
219 |
Risk Difference (M‐H, Random, 95% CI) |
‐0.02 [‐0.12, 0.09] |
1.3 EVS compared with somatostatin |
4 |
247 |
Risk Difference (M‐H, Random, 95% CI) |
‐0.03 [‐0.11, 0.06] |
1.4 EVS compared with octreotide |
8 |
1021 |
Risk Difference (M‐H, Random, 95% CI) |
‐0.01 [‐0.07, 0.05] |
2 Five‐day failure rate |
8 |
879 |
Risk Difference (M‐H, Random, 95% CI) |
‐0.03 [‐0.09, 0.02] |
2.1 EVS compared with vasopressin |
0 |
0 |
Risk Difference (M‐H, Random, 95% CI) |
0.0 [0.0, 0.0] |
2.2 EVS compared with terlipressin |
1 |
219 |
Risk Difference (M‐H, Random, 95% CI) |
‐0.02 [‐0.14, 0.11] |
2.3 EVS compared with somatostatin |
3 |
319 |
Risk Difference (M‐H, Random, 95% CI) |
‐0.03 [‐0.11, 0.06] |
2.4 EVS compared with octreotide |
4 |
341 |
Risk Difference (M‐H, Random, 95% CI) |
‐0.05 [‐0.14, 0.04] |
3 Rebleeding |
14 |
1663 |
Risk Difference (M‐H, Random, 95% CI) |
0.02 [‐0.02, 0.06] |
3.1 EVS compared with vasopressin |
1 |
64 |
Risk Difference (M‐H, Random, 95% CI) |
0.04 [‐0.17, 0.26] |
3.2 EVS compared with terlipressin |
1 |
219 |
Risk Difference (M‐H, Random, 95% CI) |
0.01 [‐0.11, 0.12] |
3.3 EVS compared with somatostatin |
4 |
359 |
Risk Difference (M‐H, Random, 95% CI) |
‐0.02 [‐0.11, 0.07] |
3.4 EVS compared with octreotide |
8 |
1021 |
Risk Difference (M‐H, Random, 95% CI) |
0.02 [‐0.04, 0.08] |
4 Rebleeding before other elective treatments |
9 |
1024 |
Risk Difference (M‐H, Random, 95% CI) |
‐0.01 [‐0.06, 0.03] |
4.1 EVS compared with vasopressin |
0 |
0 |
Risk Difference (M‐H, Random, 95% CI) |
0.0 [0.0, 0.0] |
4.2 EVS compared with terlipressin |
1 |
219 |
Risk Difference (M‐H, Random, 95% CI) |
‐0.00 [‐0.09, 0.09] |
4.3 EVS compared with somatostatin |
3 |
319 |
Risk Difference (M‐H, Random, 95% CI) |
‐0.03 [‐0.11, 0.05] |
4.4 EVS compared with octreotide |
5 |
486 |
Risk Difference (M‐H, Random, 95% CI) |
‐0.01 [‐0.07, 0.05] |
5 Mortality |
14 |
1663 |
Risk Difference (M‐H, Random, 95% CI) |
‐0.03 [‐0.07, 0.02] |
5.1 EVS compared with vasopressin |
1 |
64 |
Risk Difference (M‐H, Random, 95% CI) |
‐0.11 [‐0.34, 0.11] |
5.2 EVS compared with terlipressin |
1 |
219 |
Risk Difference (M‐H, Random, 95% CI) |
‐0.08 [‐0.19, 0.03] |
5.3 EVS compared with somatostatin |
4 |
359 |
Risk Difference (M‐H, Random, 95% CI) |
‐0.02 [‐0.10, 0.06] |
5.4 EVS compared with octreotide |
8 |
1021 |
Risk Difference (M‐H, Random, 95% CI) |
‐0.02 [‐0.08, 0.04] |
6 Mortality before other elective treatments |
7 |
681 |
Risk Difference (M‐H, Random, 95% CI) |
‐0.01 [‐0.05, 0.03] |
6.1 EVS compared with vasopressin |
0 |
0 |
Risk Difference (M‐H, Random, 95% CI) |
0.0 [0.0, 0.0] |
6.2 EVS compared with terlipressin |
0 |
0 |
Risk Difference (M‐H, Random, 95% CI) |
0.0 [0.0, 0.0] |
6.3 EVS compared with somatostatin |
2 |
150 |
Risk Difference (M‐H, Random, 95% CI) |
‐0.03 [‐0.13, 0.07] |
6.4 EVS compared with octreotide |
5 |
531 |
Risk Difference (M‐H, Random, 95% CI) |
‐0.00 [‐0.05, 0.04] |
7 Transfusions |
7 |
806 |
Mean Difference (IV, Random, 95% CI) |
‐0.35 [‐0.56, ‐0.13] |
7.1 EVS compared with vasopressin |
0 |
0 |
Mean Difference (IV, Random, 95% CI) |
0.0 [0.0, 0.0] |
7.2 EVS compared with terlipressin |
1 |
219 |
Mean Difference (IV, Random, 95% CI) |
0.20 [‐1.01, 1.41] |
7.3 EVS compared with somatostatin |
2 |
239 |
Mean Difference (IV, Random, 95% CI) |
0.48 [‐1.79, 2.75] |
7.4 EVS compared with octreotide |
4 |
348 |
Mean Difference (IV, Random, 95% CI) |
‐0.32 [‐0.75, 0.11] |
8 Adverse events |
9 |
1024 |
Risk Difference (M‐H, Random, 95% CI) |
0.11 [0.04, 0.17] |
8.1 EVS compared with vasopressin |
0 |
0 |
Risk Difference (M‐H, Random, 95% CI) |
0.0 [0.0, 0.0] |
8.2 EVS compared with terlipressin |
1 |
219 |
Risk Difference (M‐H, Random, 95% CI) |
0.10 [‐0.02, 0.21] |
8.3 EVS compared with somatostatin |
3 |
319 |
Risk Difference (M‐H, Random, 95% CI) |
0.18 [0.10, 0.26] |
8.4 EVS compared with octreotide |
5 |
486 |
Risk Difference (M‐H, Random, 95% CI) |
0.07 [‐0.04, 0.18] |
9 Serious adverse events |
4 |
538 |
Risk Difference (M‐H, Random, 95% CI) |
0.05 [0.01, 0.09] |
9.1 EVS compared with vasopressin |
0 |
0 |
Risk Difference (M‐H, Random, 95% CI) |
0.0 [0.0, 0.0] |
9.2 EVS compared with terlipressin |
1 |
219 |
Risk Difference (M‐H, Random, 95% CI) |
0.03 [‐0.03, 0.09] |
9.3 EVS compared with somatostatin |
3 |
319 |
Risk Difference (M‐H, Random, 95% CI) |
0.07 [0.01, 0.13] |
9.4 EVS compared with octreotide |
0 |
0 |
Risk Difference (M‐H, Random, 95% CI) |
0.0 [0.0, 0.0] |