| Methods |
Randomisation: computer‐generated list.
Concealment: opaque, sealed envelopes.
Treatment completed as per protocol: 98 out of 100 randomised.
Follow‐up: 30 days.
Lost to follow‐up: none.
Intention‐to‐treat analysis: no (2 patients excluded). |
| Participants |
Country: China
Cirrhotic patients with endoscopy‐proven variceal bleeding.
Exclusion: bleeding source other than oesophageal varices.
Aetiology of portal hypertension: HBsAg, alcohol, HCC, PBC, Wilson's disease. |
| Interventions |
EVS: intravariceal injections of 2 ml 3% sodium tetradecyl sulphate (max volume 20 ml).
Control: 48‐hour continuous iv infusion of octreotide 50 µg/h after an initial iv bolus of 50 µg. |
| Outcomes |
48‐hour failure to control bleeding.
48‐hour re‐bleeding.
48‐hour, in‐hospital and 30‐day mortality. |
| Notes |
|
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Adequate sequence generation? |
Low risk |
Adequate |
| Allocation concealment? |
Low risk |
Adequate |
