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. 2020 Mar 20;8:211. doi: 10.3389/fbioe.2020.00211

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Copyright © 2020 Dong, Song, Wu, Cui, Wang, Zhang and Sun.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Exocytosis of SWCNTs by primary peritoneal macrophages. (A) Representative SEM images of exosome (green arrows) and extracellular vesicles (black arrowheads) on the surface of primary peritoneal macrophages at 24 h (Left) and 36 h (Right) after 6 h SWCNT exposure. (B) TEM images showing the SWCNTs (yellow arrows), small vesicles (red arrows), multivesicular bodies (MVBs, orange arrows) and autophagosome/autolysosome (pink arrows) in primary macrophages at 1 2 h (up panels) and 36 h (bottom panels) after removing 12 h SWCNTs (10 μg/mL) exposure. (C) NIR spectra of the supernatant of SWCNTs at different time (8–48 h). (D) SEM image of primary macrophages phagocytosis tangled SWCNTs.