Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Mar 20;8:220. doi: 10.3389/fbioe.2020.00220

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2020 Chakraborty, George, Tripathi, Levine and Jolly.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Distinguishing between hybrid E/M cells vs. mixtures of E and M cells. (A) Scatter plot showing CCLE cell lines that display a hybrid E/M phenotype (red) on the mixture curve (dotted curve) determined by the mean of 35 pure E (orange) and pure M (blue) reference samples in CCLE dataset. (B) Scatter plot showing the 100 farthest (purple) and 100 closest (green) samples based on the distance from the mixture curve. (C) Bar plots showing EMT scores of N (10, 20, 50, and 100) closest and farthest hybrid E/M samples from mixture curve. (D) Mesenchymal proportion (%M) distribution of the 100 closest and farthest hybrid samples from mixture curve. *p < 0.05, N = 10, 20, 50 and 100, two-tailed Student’s t-test; error bars represent standard deviation.