Figure 2. The consensus hub substructure from all and individual clathrin cage architectures.
(a) The domain structure of the clathrin heavy and light chains. (b) The consensus hub structure resulting from subparticle refinement of all cage types at 4.7 Å resolution. The domain structure is coloured according to (a) and the unsharpened density is shown as transparent. (c) The consensus map density and model between HCR6c-7c are shown as well as (d) the gold-standard FSC curves for the consensus hub structure and each cage type with its respective hub substructure.