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. Author manuscript; available in PMC: 2020 Nov 1.
Published in final edited form as: Alcohol. 2018 Jul 26;80:17–24. doi: 10.1016/j.alcohol.2018.07.010

Fig. 4. Alcohol feeding in mice potentiates and sustains RSV-induced PKC epsilon auto-downregulation.

Fig. 4.

PKCε activity was assayed in the same mouse tracheal epithelial samples from in vivo-exposed mice shown in Fig.3. RSV infection decreased PKCε activity (bp<0.05 vs Control mice at 24–48 hr), but returned to baseline by day 3–7. Decreased PKCε activity below baseline levels (autodownregulation) after RSV infection persisted in EtOH-fed mice (ap<0.01 vs RSV only at 72 hr -1 wk and Control mice at all times). n=6–10 mice per group from replicated experiments.