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. 2020 Mar 20;11:422. doi: 10.3389/fimmu.2020.00422

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Copyright © 2020 Lia, Di Vito, Cerrano, Brunello, Calcaterra, Tapparo, Giaccone, Mavilio and Bruno.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Potential application of extracellular vesicles in allografting. Red arrows represent potential effect of infused EVs; green arrows represent potential application of EVs as biomarkers. HSC, hematopoietic stem cells; HCT, hematopoietic cell transplantation; EVs, extracellular vesicles; MSCs, mesenchymal stromal cells; GvL, graft-versus-leukemia; GvHD, graft-versus-host disease.