Table 1.
Baseline characteristics of 132 patients with pneumococcal community-acquired pneumonia (CAP)
| Variables | Value |
|---|---|
| Age (years) | 49.5 ± 21.6 |
| Gender ratio (male/female) | 4.7 (109/23) |
| Comorbidities | 81 (61.4) |
| Pulmonary disease | 67 (54.5) |
| Chronic obstructive pulmonary disease | 51 (38.6) |
| Heart disease | 27 (20.5) |
| Diabetes mellitus | 21 (16) |
| Current smoking | 79 (60) |
| Prior antibiotherapy | 39 (29.5) |
| SAPS II | 32.8 ± 18.6 |
| SOFA | 2 (0–22) |
| CURB-65 | 2 (0–5) |
| PSI class II and III | 60 (45.5) |
| PSI class IV | 35 (26.5) |
| PSI class V | 37 (28) |
| Signs of severity at admission | |
| Acute renal failure | 63 (47.7) |
| Septic shock | 35 (26.5) |
| ALI/ARDS | 30 (22.7) |
| Mechanical ventilation | 62 (47) |
| Multiple organ failure | 19 (14.4) |
| Leukocyte count (×109/l) | 17.3 ± 8.4 |
| C-reactive protein (mg/l) | 163.3 ± 89.4 |
| Serum glucose (mmol/l) | 8.9 ± 5.6 |
| Serum creatinine (μmol/l) | 122.3 ± 94.3 |
| Serum lactate (mmol/l) | 6.9 ± 7.1 |
| Arterial pH | 7.35 ± 0.13 |
| PaO2/FiO2 | 244 ± 82.6 |
| Chest radiograph at admission | |
| Alveolar infiltrates | 132 (100) |
| Interstitial infiltrates | 34 (25.8) |
| Bilateral involvement | 52 (39.4) |
| Multilobar involvement | 64 (48.5) |
| Pleural effusion | 31 (23.5) |
Data are presented as number (%) or mean ± SD or median (extreme)
SAPS Simplified Acute Physiology Score, SOFA Sequential Organ Failure Assessment, PSI pneumonia severity index, ALI acute lung injury, ARDS acute respiratory distress syndrome, PaO 2 partial pressure of oxygen in arterial blood, FiO 2 fraction of inspired oxygen