Table 1. Characteristics of the subset of the UPBEAT cohort use for this study. Diagnosis of GDM was made using IADPSG thresholds (18).
Cohort |
No GDM |
GDM |
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Factor | Cat. | No. | Mean | Std. dev. | Min. | Max. | No. | Mean | Std. dev. | Min. | Max. | No. | Mean | Std. dev. | Min. | Max. | p-Value |
Maternal BMIa | 831 | 36.27 | 4.8 | 30 | 63.4 | 582 | 35.88 | 4.43 | 30 | 59.9 | 249 | 37.18 | 5.47 | 30 | 63.4 | <0.001 | |
Maternal agea | 831 | 30.73 | 5.4 | 16 | 45 | 582 | 30.24 | 5.63 | 16 | 45 | 249 | 31.88 | 4.62 | 18 | 44 | <0.001 | |
BGC (mM) | Fasting | 831 | 4.75 | 0.56 | 3.5 | 8.4 | 582 | 4.52 | 0.31 | 3.5 | 5 | 249 | 5.31 | 0.6 | 3.9 | 8.4 | <0.001 |
BGC (mM) | 1 h | 831 | 8.05 | 2.13 | 2.6 | 17.6 | 582 | 7.21 | 1.42 | 2.6 | 9.9 | 249 | 10 | 2.22 | 4.1 | 17.6 | <0.001 |
BGC (mM) | 2 h | 831 | 6 | 1.53 | 2.4 | 14.6 | 582 | 5.55 | 1.14 | 2.4 | 8.4 | 249 | 7.06 | 1.79 | 3 | 14.6 | <0.001 |
HbA1C (%) | 782 | 4.85 | 0.35 | 3.89 | 6.61 | 546 | 4.79 | 0.33 | 3.89 | 5.78 | 238 | 4.97 | 0.37 | 4.14 | 6.61 | <0.001 | |
HbA1C (mMol M–1) | 782 | 29.49 | 3.85 | 19 | 48.7 | 546 | 28.89 | 3.61 | 19 | 39.7 | 238 | 30.86 | 4.05 | 21.7 | 48.7 | <0.001 | |
No. | % | Cum. (%) | |||||||||||||||
Sex of infant | Male | 429 | 51.6 | — | — | — | 308 | — | — | — | — | 121 | — | — | — | — | 0.254 |
Ethnicity | Black | 169 | 20.34 | 20.34 | — | — | |||||||||||
White | 563 | 67.75 | 88.09 | — | — | ||||||||||||
Asian | 54 | 6.5 | 94.59 | — | — | ||||||||||||
Other | 45 | 5.42 | 100 | — | — | ||||||||||||
Parity | 0 | 379 | 45.61 | 45.61 | — | — | |||||||||||
1 | 265 | 31.89 | 77.5 | — | — | ||||||||||||
2 | 121 | 14.56 | 92.06 | — | — | ||||||||||||
3 | 43 | 5.17 | 97.23 | — | — | ||||||||||||
4 | 15 | 1.81 | 99.04 | — | — | ||||||||||||
5 | 6 | 0.72 | 99.76 | — | — | ||||||||||||
7 | 2 | 0.24 | 100 | — | — | ||||||||||||
Pre-eclampsia | 772 | 59 | |||||||||||||||
Study Arm | Control | 415 | 49.94 | ||||||||||||||
Intervention | 416 | 50.06 |
At 17 weeks gestation. BGC, blood glucose concentration. Ethnicity is maternal.