Table 3.
Heart rate variability analysis
| Active | Control | Outcome (3 and 6 months combined) | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Outcome | Baseline (N=12) | 3 months (N=10) | 6 months (N=13) | Baseline (N=12) | 3 months (N=11) | 6 months (N=10) | Ratio of medians (Active vs. sham) | 95% CI | p-value |
| RMSSD (ms) | 20.2 (14.6 – 31.7) | 17.0 (10.0 – 26.5) | 12.3 (8.5 – 30.7) | 18.2 (12.5 – 28.5) | 17.1 (15.6 – 50.9) | 27.0 (13.4 – 41.7) | 0.71 | 0.45 – 1.12 | 0.15 |
| SDNN (ms) | 17.7 (12.0 – 23.8) | 15.9 (14.4 – 23.2) | 20.1 (7.4 – 33.3) | 15.3 (11.5 – 28.5) | 19.1 (13.0 – 37.6) | 20.8 (12.4 – 25.9) | 0.82 | 0.54 – 1.25 | 0.36 |
| pNN50 (%) | 1.2 (0 – 14.0) | 1.3 (0 – 5.7) | 0 (0 – 10.8) | 0.5 (0 – 9.0) | 1.4 (0 – 14.9) | 8.5 (0 – 20.1) | 0.38 | 0.06 – 2.36 | 0.23 |
| LF power (n.u.) | 55.5 (34.4 – 59.9) | 52.2 (34.6 – 81.8) | 50.2 (39.1 – 64.1) | 39.0 (16.4 – 73.5) | 20.5 (13.3 – 48.7) | 42.0 (20.9 – 56.6) | 1.59 | 1.14 – 2.23 | 0.007 |
| HF power (n.u.) | 44.4 (40.0 – 65.5) | 47.6 (18.0 – 65.4) | 49.7 (35.8 – 60.3) | 60.8 (26.3 – 83.4) | 79.5 (51.1 – 86.5) | 57.7 (43.4 – 78.9) | 0.74 | 0.59 – 0.93 | 0.010 |
| LF/HF ratio | 1.3 (0.5 – 1.5) | 1.1 (0.5 – 4.5) | 1.0 (0.6 – 1.8) | 0.6 (0.2 – 2.8) | 0.3 (0.2 – 10) | 0.7 (0.3 – 13) | 2.16 | 1.29 – 3.63 | 0.003 |
Data are presented as median (interquartile range). N.u. = normalized units