Table 2. t-test comparing the expression levels between rhythmic (p-value ≤ 0.005) and non-rhythmic genes (randomly chosen same number of genes among those with p-value > 0.01), in mouse liver dataset (microarray).

Method	group	n	Mean
ARS	rhythmic	4019	1151.2
	non-rhythmic	4019	383.6
t-test t = 25.4 p <2.2e–16 df = 7021.4
meta2d	rhythmic	4520	1113.2
	non-rhythmic	4520	398.5
t-test t = 24.8 p <2.2e–16 df = 8050.1
empJTK	rhythmic	3373	1113.9
	non-rhythmic	3373	442.5
t-test t = 20.1 p <2.2e–16 df = 6260.8
RAIN	rhythmic	5044	1066.3
	non-rhythmic	5044	384.2
t-test t = 25.4 p <2.2e–16 df = 8935.3
JTK	rhythmic	2646	1214.4
	non-rhythmic	2646	454.3
t-test t = 19.6 p <2.2e–16 df = 4742.9
LS	rhythmic	736	1500.3
	non-rhythmic	736	526.5
t-test t = 12.6 p <2.2e–16 df = 1351.2
GeneCycle	rhythmic	4145	1082.8
	non-rhythmic	4145	425.6
t-test t = 22.0 p <2.2e–16 df = 7622.8