Table 3.
Difference in the mean of total cigarettes per day for the four VLNC conditions vs. NNC controls at the Week 6 visit among participants included in cigarette butt analysis.
Unadjusted Linear Regression1 | Adjusted Linear Regression2 | ||||
---|---|---|---|---|---|
Treatment Group | N | Mean Difference (95% CI) | p-value | Mean Difference 5% CI) | p-value |
15.8 mg/g | 64 | ||||
5.2 mg/g | 66 | 1.04 (−3.22, 5.29) | 0.63 | 0.67 (−3.34, 4.69) | 0.74 |
2.4 mg/g | 51 | −5.32 (−9.87, −0.77) | 0.02 | −5.91 (−10.19, −1.62) | 0.007 |
1.3 mg/g | 64 | −4.56 (−8.84, −0.27) | 0.04 | −4.55 (−8.58, −0.51) | 0.03 |
0.4 mg/g | 62 | −6.59 (−10.91, −2.27) | 0.003 | −7.33 (−11.42, −3.23) | <0.001 |
0.4 mg/g HT | 70 | −4.61 (−8.81, −0.42) | 0.03 | −5.28 (−9.26, −1.3) | 0.0096 |
Adjusted for baseline cigarettes per day
Adjusted for age, race, gender and salivary nicotine metabolite ratio