Goto 2012.
Methods | Retrospective review | |
Participants | 53 patients with gynaecological malignancy and malignant bowel obstruction due to disease progression or recurrence between 2005 and 2010 Excluded: "cases with symptoms of bowel obstruction which were temporary and restorable with short medical treatment were excluded" |
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Interventions | 33 patients pharmacological treatment 20 patients laparotomy: colostomy 11; ileostomy 7; bypass 7 |
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Outcomes | Successful palliation defined as: ability to eat solid food for at least 60 days Surgical group: achieved 70% (14/20); symptoms unrelieved 10% (2/20) Postoperative complications 35% (7/20): infections and wound dehiscence 15% (3/20); abscess 20% (4/20); sepsis 5% (1/20); DVT 5% (1/20); short bowel syndrome 5% (1/20) Postoperative mortality within 30 days: 5% (1/20) Median survival following diagnosis of MBO operative: 146 days (61 to 294) Median survival following diagnosis of MBO non‐operative: 69 days |
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Notes | Operative group selected as fit for surgery and did better | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | High risk | "Of all the patients with gynaecological malignancy treated at our institute, medical records of patients who presented with MBO due to disease progression or recurrence between 2005 and 2010 were reviewed." |
Allocation concealment (selection bias) | High risk | "Of all the patients with gynaecological malignancy treated at our institute, medical records of patients who presented with MBO due to disease progression or recurrence between 2005 and 2010 were reviewed." |
Blinding (performance bias and detection bias) All outcomes | High risk | "Of all the patients with gynaecological malignancy treated at our institute, medical records of patients who presented with MBO due to disease progression or recurrence between 2005 and 2010 were reviewed." |
Blinding of participants and personnel (performance bias) All outcomes | High risk | "Of all the patients with gynaecological malignancy treated at our institute, medical records of patients who presented with MBO due to disease progression or recurrence between 2005 and 2010 were reviewed." |
Blinding of outcome assessment (detection bias) All outcomes | High risk | "Of all the patients with gynaecological malignancy treated at our institute, medical records of patients who presented with MBO due to disease progression or recurrence between 2005 and 2010 were reviewed." |
Selective reporting (reporting bias) | Unclear risk | All patient outcomes reported for surgical group Conservative treatment group data limited Results not reported according to surgical intervention |