Mangili 2005.

Methods	Retrospective case series
Participants	47 women with intestinal obstruction secondary to ovarian cancer
Interventions	Non‐randomised 27 patients surgery: 4 inoperable, 2 gastrointestinal tubes placed, 8 colostomies, 9 intestinal bypass, 3 intestinal resections, 1 bypass and colostomy 20 patients medical management with octreotide: mean dosage of 0.48 mg/day; 1 required nasogastric tube
Outcomes	30‐day mortality post‐surgery 22% Post‐surgery morbidity 22% (6 patients): 2 wound infection, 2 incisional dehiscence, 2 enterocutaneous fistula Mean survival (surgical and non‐surgical): 76 days Multivariant analysis showed women treated with surgery had significantly better survival than women treated with octreotide (P value < 0.001) after adjustment for performance status (and other prognotic factors) but no hazard ratio reported
Notes	Prognostic factors reported therefore possible to assess baseline imbalances; only performance status (PS 0, 1, 2) differed significantly (P value = 0.03)
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	High risk	Patients allocated to surgery by clinician/patient choice and retrospectively reviewed
Allocation concealment (selection bias)	High risk	Patients allocated to surgery by clinician/patient choice and retrospectively reviewed
Blinding (performance bias and detection bias) All outcomes	High risk	Not reported; probably not done
Blinding of participants and personnel (performance bias) All outcomes	High risk	Not reported; probably not done
Blinding of outcome assessment (detection bias) All outcomes	High risk	Not reported; probably not done
Selective reporting (reporting bias)	Unclear risk	Some outcomes analysed with statistical adjustment for the differences in prognostic factors within the group and others not. When statistically significant, hazard ratio not presented