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. 2016 Jan 4;2016(1):CD002764. doi: 10.1002/14651858.CD002764.pub2

Mooney 2013.

Methods Retrospective review
Participants 1518 1C‐IV ovarian carcinoma with bowel obstruction
Interventions Surgical management 373, non‐surgical management 1145
Outcomes Median survival after first post‐diagnosis obstruction: surgical 162 days; non‐surgical 98 days, P value < 0.001
30‐day mortality; surgical 13.1%; non‐surgical 24.2%, P value < 0.001
Days in hospital, median (IQR): surgical 24 (16, 42), non‐surgical 17 (8, 32), P value < 0.001
Days out of hospital, median (IQR): surgical 137 (29, 536); non‐surgical 80 (17, 412), P value < 0.002
Ratio of days out to days in hospital: surgical 6.2:1; non‐surgical 5.3:1, P value = 0.28
Re‐admission for obstruction: surgical 33.5%; non‐surgical 35.9%, P value = 0.403
Notes Uses Surveillance, Epidemiology, and End Results ‐ Medicare database that tracks 26% of patients with cancer in the US population by searching for coded information on billing for procedures and services rendered
Hospitalisation and re‐admission rates used as a proxy for quality of life markers
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) High risk Coding/billing information reflected that patients were allocated to surgery by clinician/patient choice and retrospectively reviewed
Allocation concealment (selection bias) High risk Coding/billing information reflected that patients were allocated to surgery by clinician/patient choice and retrospectively reviewed
Blinding (performance bias and detection bias) 
 All outcomes High risk Coding/billing information reflected that patients were allocated to surgery by clinician/patient choice and retrospectively reviewed
Blinding of participants and personnel (performance bias) 
 All outcomes High risk Coding/billing information reflected that patients were allocated to surgery by clinician/patient choice and retrospectively reviewed
Blinding of outcome assessment (detection bias) 
 All outcomes High risk Coding/billing information reflected that patients were allocated to surgery by clinician/patient choice and retrospectively reviewed
Selective reporting (reporting bias) Unclear risk Not reported by surgical procedure ‐ unclear it this information was available via coding or not