Mooney 2013.
Methods | Retrospective review | |
Participants | 1518 1C‐IV ovarian carcinoma with bowel obstruction | |
Interventions | Surgical management 373, non‐surgical management 1145 | |
Outcomes | Median survival after first post‐diagnosis obstruction: surgical 162 days; non‐surgical 98 days, P value < 0.001 30‐day mortality; surgical 13.1%; non‐surgical 24.2%, P value < 0.001 Days in hospital, median (IQR): surgical 24 (16, 42), non‐surgical 17 (8, 32), P value < 0.001 Days out of hospital, median (IQR): surgical 137 (29, 536); non‐surgical 80 (17, 412), P value < 0.002 Ratio of days out to days in hospital: surgical 6.2:1; non‐surgical 5.3:1, P value = 0.28 Re‐admission for obstruction: surgical 33.5%; non‐surgical 35.9%, P value = 0.403 |
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Notes | Uses Surveillance, Epidemiology, and End Results ‐ Medicare database that tracks 26% of patients with cancer in the US population by searching for coded information on billing for procedures and services rendered Hospitalisation and re‐admission rates used as a proxy for quality of life markers |
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Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | High risk | Coding/billing information reflected that patients were allocated to surgery by clinician/patient choice and retrospectively reviewed |
Allocation concealment (selection bias) | High risk | Coding/billing information reflected that patients were allocated to surgery by clinician/patient choice and retrospectively reviewed |
Blinding (performance bias and detection bias) All outcomes | High risk | Coding/billing information reflected that patients were allocated to surgery by clinician/patient choice and retrospectively reviewed |
Blinding of participants and personnel (performance bias) All outcomes | High risk | Coding/billing information reflected that patients were allocated to surgery by clinician/patient choice and retrospectively reviewed |
Blinding of outcome assessment (detection bias) All outcomes | High risk | Coding/billing information reflected that patients were allocated to surgery by clinician/patient choice and retrospectively reviewed |
Selective reporting (reporting bias) | Unclear risk | Not reported by surgical procedure ‐ unclear it this information was available via coding or not |