Parveen 2009.
Methods | Retrospective case series | |
Participants | 56 patients presenting to 3 surgical units with partial or complete obstruction on a background of ovarian cancer from March 1998 to April 2009 | |
Interventions | Trial of conservative management to all patients first: IV fluids, anti‐spasmodics, nasogastric tube, nil by mouth 22 patients: conservative management successful 30 patients: conservative management unsuccessful and proceeded to laparotomy. Specifically: resection and anastomosis 9; bypass surgery 7; colostomy 3; Hartmann procedure 1; adhesiolysis 8; open/close 2 (advanced abdominal malignancy) 4 patients: conservative management unsuccessful but laparotomy not done due to uncontrolled ascites and cachexia |
|
Outcomes | Conservative treatment: sufficient 39% (22/56) Surgical treatment "successful", i.e. symptomatic relief and return of bowel function: 26.7% (8/30) Postoperative mortality: 40% (12/30): mean survival after operation 4.2 months (range 2 to 6 months) Postoperative complications: 86.6% (26/30): wound infection 77% (22/30); UTI 23% (6/30); intra‐abdominal abscess 15% (4/30); burst abdomen 7.6% (2/30); enterocutaneous fistula 7.6% (2/30); pneumonia 7.6% (2/30); DVT 7.6% (2/30) |
|
Notes | 8 of the 30 surgical patients had lysis of adhesions | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | High risk | "Laparotomy was done if obstruction was not relieved by conservative treatment." |
Allocation concealment (selection bias) | High risk | "Laparotomy was done if obstruction was not relieved by conservative treatment." |
Blinding (performance bias and detection bias) All outcomes | High risk | "The record of all patients admitted in all three surgical units of Ayub Teaching Hospital from March 1998 to April 2008 with a diagnosis of intestinal obstruction were reviewed." |
Blinding of participants and personnel (performance bias) All outcomes | High risk | "The record of all patients admitted in all three surgical units of Ayub Teaching Hospital from March 1998 to April 2008 with a diagnosis of intestinal obstruction were reviewed." |
Blinding of outcome assessment (detection bias) All outcomes | High risk | "The record of all patients admitted in all three surgical units of Ayub Teaching Hospital from March 1998 to April 2008 with a diagnosis of intestinal obstruction were reviewed." |
Selective reporting (reporting bias) | High risk | All patients accounted for Results not reported according to surgical intervention 8 patients underwent surgery for non‐malignant obstruction and were included in the outcomes |