Pecorelli 1994.
Methods | Retrospective review | |
Participants | 147 patients from 1973 to 1983; all patients had recurrent ovarian carcinoma | |
Interventions | 117 patients had a definite procedure; 30 patients no surgical correction | |
Outcomes | "Benefit of surgery" defined as able to leave hospital on a regular/low residue diet: 83/117 (71%) Perioperative mortality: 15/117 (13%) for corrective surgery; 23/147 (16%) for total Median survival: 3.5 months, mean 7.2 (? group) | |
Notes | Intestinal resections in 13%, bypass in 17% and neostomy in 50% Benefit of surgery not synonymous with relief of symptoms as suggested |
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Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | High risk | Patients allocated to surgery by clinician/patient choice and retrospectively reviewed |
Allocation concealment (selection bias) | High risk | Patients allocated to surgery by clinician/patient choice and retrospectively reviewed |
Blinding (performance bias and detection bias) All outcomes | High risk | Patients allocated to surgery by clinician/patient choice and retrospectively reviewed |
Blinding of participants and personnel (performance bias) All outcomes | High risk | Patients allocated to surgery by clinician/patient choice and retrospectively reviewed |
Blinding of outcome assessment (detection bias) All outcomes | High risk | Patients allocated to surgery by clinician/patient choice and retrospectively reviewed |
Selective reporting (reporting bias) | Unclear risk | Median survival reported as 3.5 months but the group this is based on is not stated |