Pothuri 2003.
| Methods | Retrospective review | |
| Participants | 68 operations on 64 patients; ovarian cancer | |
| Interventions | Surgery for all patients 1 exploratory laparotomy, 11 exploratory laparotomy and G‐tube/PEG insertion, 10 G tube insertions, 21 colostomies, 18 resections and 33 bypasses |
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| Outcomes | 37 of 52 patients tolerated a regular or low residue diet 60 days postoperatively; 22% morbidity including 5 enteric fistulae, 5 abscesses, 2 pulmonary embolus, 2 bacterial peritonitis, 1 neutropenic fever 36/57 (63%) patients who had surgical correction re‐obstructed Mean time to re‐obstruction 4.5 months (14 days to 16 months) Median survival for all patients was 7.9 months For those in whom surgical correction was possible median survival was 8.4 months versus 3.5 months where surgical correction was not possible For those successfully palliated median survival was 11.6 months versus 3.9 months where it was not successful (P value < 0.01) For patients with small bowel obstruction median survival was 7.4 months, large bowel obstruction median survival was 7.7 months or both median survival was 9.7 months |
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| Notes | — | |
| Risk of bias | ||
| Bias | Authors' judgement | Support for judgement |
| Random sequence generation (selection bias) | High risk | "We retrospectively reviewed all patients undergoing surgery for intestinal obstruction due to recurrent ovarian cancer from 1994‐1999." |
| Allocation concealment (selection bias) | High risk | "We retrospectively reviewed all patients undergoing surgery for intestinal obstruction due to recurrent ovarian cancer from 1994‐1999." |
| Blinding (performance bias and detection bias) All outcomes | High risk | "We retrospectively reviewed all patients undergoing surgery for intestinal obstruction due to recurrent ovarian cancer from 1994‐1999." |
| Blinding of participants and personnel (performance bias) All outcomes | High risk | "We retrospectively reviewed all patients undergoing surgery for intestinal obstruction due to recurrent ovarian cancer from 1994‐1999." |
| Blinding of outcome assessment (detection bias) All outcomes | High risk | "We retrospectively reviewed all patients undergoing surgery for intestinal obstruction due to recurrent ovarian cancer from 1994‐1999." |
| Selective reporting (reporting bias) | Unclear risk | Outcomes reported specifically for patients with bowel obstruction due to recurrent ovarian carcinoma Outcome reported for all 68 operations on 64 patients Results not reported according to surgical intervention |