Table 4.

Clinical and Biochemical Pregnancies in Women with Crohn’s Disease Prescribed Corticosteroid Three Months Prior to Embryo Transfer, Compared to Those Without a Corticosteroid Prescription

	Exposed Cohort (Steroid Use Prior to Embryo Transfers)		Unexposed Cohort (No Steroid Use Prior to Embryo Transfers)		Crude OR (95% CI)	Adjusted OR (95% CI)c
Biochemical pregnancy (positive hCG)a
Yes, N (%)	39	(34.8)	305	(31.8)	1.25 (0.79–1.99)	1.04 (0.61–1.77)
No, N (%)	73	(65.2)	654	(68.2)
Clinical Pregnancy (positive ultra sound)b
Yes, N (%)	29	(76.3)	255	(83.9)	0.60 (0.26–1.42)	0.66 (0.22–1.95)
No, N (%)	9	(23.7)	49	(16.1)

Notes: ^aNumber of embryo transfers in the exposed cohort: 114 (number of women: 60) and unexposed cohort: 964 (number of women: 354). ^bNumber of embryo transfers in the exposed cohort: 39 (number of women: 31) and unexposed cohort: 305 (number of women: 215). ^cAdjusted for Charlson Index, women’s age, calendar year of treatment, type of treatment (IVF, ICSI, FET), cause of infertility (female factor, male factor, or mixture of factors/idiopathic), BMI, partner´s age, smoking, alcohol and use of IBD medication (azathrioprine/mercaptopurine, Aminosalicylic acid and TNF-α inhibitors) 6 months prior to embryo transfer.