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. 2020 Feb 27;5(4):e131018. doi: 10.1172/jci.insight.131018

Figure 2. Frequency of somatic variants in bone marrow samples from patients with SDS and FA and healthy control subjects.

Figure 2

(A) Comparison of average (±SEM) variant rate between FA (n = 6), SDS (n = 7), and healthy control subjects (n = 6). The box plots depict the minimum and maximum values (whiskers), the upper and lower quartiles, and the median. The length of the box represents the interquartile range. Results by Student’s t test are shown. P = 0.0695 by Kruskal-Wallis test with Dunn’s post hoc test when comparing the 3 subject groups. (B–D) Variant rate among controls, FA subjects, and SDS subjects organized according to ages. (E) Allele frequency of the various variants in controls, FA subjects, and SDS subjects. The groups were compared using the Wilcoxon’s signed-rank test. *P < 0.0001. The y axis represents the variant frequency and the x axis represents the variants arranged from those with the highest allele frequency to the lowest. In each group, each number may represent a different variant.