Skip to main content
. Author manuscript; available in PMC: 2020 Jul 20.
Published in final edited form as: Nat Neurosci. 2020 Jan 20;23(3):433–442. doi: 10.1038/s41593-019-0576-z

Fig. 1. Neuronal organization and computations in the OB.

Fig. 1

a, Schematic illustration of whitening in the OB. Top: correlated input patterns with different variance. Bottom: decorrelated output patterns with similar variance. Center: Highly simplified illustration of the OB circuit. MCs receive excitatory input from a single glomerulus and interact via inhibitory INs. Whitening requires multisynaptic interactions between specific subsets of MCs that are mediated by INs and defined by the wiring diagram. Interactions between INs and top-down inputs to the OB are not shown. b, Example of a reciprocal synapse between a MC and an IN. c, Reconstructions of a MC (left) and an IN (right). Gray volumes show glomeruli, dots depict synapses, colors denote synapse class (unidirectional non-sensory input [blue], unidirectional output [red], reciprocal [magenta], input from sensory neurons [green]). d, Simplified representation of the wiring diagram between MCs and INs (binarized connection strength). Colored matrix elements show MC→IN synapses (blue), MC←IN synapses (orange), and reciprocal synapses (black).