Figure 7. Comparison with other epistasis detection methods.
(a) Correlation between Fisher exact test P value and SuperDCA coupling strength (red and blue for ecogroup 1a (EG1a) and non-EG1a SNPs, respectively), and between Fisher exact test P value and SpydrPick mutual information (green). (b) Overlap of strong linked SNP sites detected by Fisher exact test (p<10−10, excluding EG1a SNPs) and SuperDCA (coupling strength >10-2.2). Red for interacted SNP pairs detected by both methods, blue for SNP pairs detected only by Fisher exact test.
Figure 7—figure supplement 1. EG1a interactions that only detected by Fisher exact test.
