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. Author manuscript; available in PMC: 2021 Mar 25.
Published in final edited form as: Chem Rev. 2019 Nov 27;120(6):3051–3126. doi: 10.1021/acs.chemrev.9b00450

Figure 16.

Figure 16.

Common sites for splitting inteins. a) Commonly explored sites for splitting the intein domain in the IntN (S1, S2, S3) and IntC (S10, S11) domains as well as the location of the endonuclease domain (EN/S0). β-strands (β1-β12) are indicated by grey arrows. Split site numbered according to Sun et al.377 b) Split sites mapped onto the structure of the Ssp DnaB mini-intein (PBD ID: 1MI8). The canonical IntN and IntC subdomains (i.e. the S0 split site) are colored light brown and orange respectively.