Fig. 2.

Hepatic expression of genes related to lipid metabolism, FXR and Toll-like receptors in women with morbid obesity (n = 82) classified according to liver histopathology: normal liver (NL), simple steatosis (SS), and non-alcoholic steatohepatitis (NASH). The Mann-Whitney U test or Kruskal-Wallis test was used to determine differences between groups. SREBP2, sterol regulatory element-binding protein 2; ABCA1, ATP-binding cassette A1; ABCG, ATP-binding cassette G; CPT1α, carnitine palmitoyl transferase 1 alpha; CROT, carnitine O-Octanoyltransferase; SREBP1C, sterol regulatory element-binding protein 1c; PPARα, peroxisome proliferator-activated receptor alpha; LXRα, liver X receptor alpha; ACC1, acetyl-CoA carboxylase 1; FAS, fatty acid synthase; FXR, farnesoid X receptor; TLR2, Toll-like receptor 2; TLR4, Toll-like receptor 4; and TLR9, Toll-like receptor 9. p < 0.05 was considered statistically significant